astraveus-logo-header

Revolutionizing Cell Therapy Processing

Our Technology

The Lakhesys™ Benchtop Cell Factory: Innovation at the cellular level

Empowering the Next Generation of Cell Therapies with the Lakhesys™ Benchtop Cell Factory. Join us in enabling the advancement of cell therapies by minimizing process development effort and maximizing manufacturing output.

Lakhesys™ Addresses the
Challenges of Cell Therapy Manufacturing

Empowering the Next Generation of Cell Therapies with the Lakhesys™ Benchtop Cell Factory. Join us in enabling the advancement of cell therapies by minimizing process development effort and maximizing manufacturing output.

Cell Functionality Maximization

Process
Optimization

Consistent
Scaling

Advantages of
Lakhesys™ Benchtop Cell Factory

The Lakhesys™ Benchtop Cell Factory offers unparalleled advantages in the realm of cell and gene therapies. From enhancing process optimization to maximizing facility output, discover how we are setting new standards in cell therapy processing.

astraveus-lakhesys-benchtop-cell-factory

Integrated online analytics
Automated image-based cytometry, PAT sensors, etc.

Transforming cells into powerful therapeutics
Array of high accuracy and efficiency microfluidic bioprocessors (Lakhesys™ units)

Full digitization
Total workflow integration into a unique, remotely accessible software

Compatible with non-adherent cells such as (CAR-) T, NK and HSC modalities

astravues icon circle checkmark

Compatible and demonstrated for non-adherent cells including (CAR-) T, NK, HSC

astravues icon circle checkmark

Compatible with adherent cell processing

astravues icon circle checkmark

Amenable to iPSC processes in the future

Autologous Cell Therapy Process in Lakhesys™ Benchtop Cell Factory

Improving End-to-End Manufacturing through Miniaturization

astraveus-process-icon-1

Magnetic Enrichment

astraveus-process-icon-2

Microfluidic Enrichment

astraveus-process-icon-3

Activation

astraveus-process-icon-4

Transduction

astraveus-process-icon-5

Washing

astraveus-process-icon-6

Expansion

astraveus-process-icon-7

Formulation

astraveus-process-icon-8

Product output

Why Microfluidics?

Microfluidics for
best-in-class cell processing

1000x

Less microfluidic Routing Volume

Lakhesys™ technology minimizes “useless” reagent consumption to fill and prime non-processing space.

1000x

Stronger Cell-Reactant Contact

Maximizing speed and yield of all reaction steps compared to flasks or other settled culture conditions.

35x

More conditions

Optimization of multiple critical process parameters in a DoE setting

10⁶ to 10⁹

Bioprocessor Cell Capacity

Process can be linearly scaled down to proportionally reduce reactant consumption while maintaining process parameters.

astraveus-gas-transfer

Publications

Have questions or ideas? Reach out to Astraveus to learn more about our groundbreaking work in biotechnology, or to explore partnership opportunities.

79, Avenue de Fontainebleau
94270 Le Kremlin-Bicêtre
France